What was supposed to be a day filled with fun and joy turned into a tragic incident for the grad-student at The University of Georgia, Aimee Copeland.
That day in 2012, she and her friends decided to go on a trip to a small lake, where they could zipline over the water. This sounded like a great idea which they all loved the moment they heard it.
Unfortunately, when it was Aimee’s turn to have some fun, the the cable snapped and she fell down a cliff. Sadly, she lost her leg that day.
Aimee was rushed to the hospital, and once there doctors had more horrific news. Aimme contracted a very serious flesh-eating bacteria which infected her wound. It was a matter of hours if she would survive or live.
The bacteria she had is known as Aeromonas hydrophila. This bacteria easily leads to a life-threatening condition known as necrotizing fasciitis, commonly referred to as a flesh-eating disease.
It required 11 surgeries for her life to be saved, but she lost both her hands and legs which needed to be amputated.
However, as brave as she has been, this young woman didn’t let the tragedy stay on her way of living her life to the best of her abilities.
Four years after the incident, Aimee shared a photo of herself at the beach, wearing a bikini and putting a huge smile on her face.
Many found inspiration in the photo and it was soon shared on the social media thousands of times with many saying that Aimee is a true inspiration.
She’s proud of herself and of everything she managed to overcome, and what’s most, she’s proud of her body and the way she looks after the ordeal she had gone through.
“It has taken me a long time to become comfortable with and accept my new body. We are ALL made with imperfections and there is so much beauty in our flaws. The scars and skin grafting build character! It’s not about what you have — what you do with what you have is what really counts,” she wrote in the caption.
Today, Aimee is an advocate for amputee and disability rights, and she continues to inspire others through her public speaking engagements and social media posts. What’s most, she’s pursuing a PhD in psychology at the University of West Georgia.
She is the perfect example that nothing can take our dreams away, not even a tragedy like the one she suffered.
If you want to learn more about this gorgeous young lady check out the video below.
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
Leave a Reply