He never even knew my name until one day, he did. Suddenly, the most charismatic man in the office was everywhere, flashing his perfect smile and asking me out. But why now? Something didn’t add up. And when I finally discovered the reason, it shattered me.
When no one notices you, at first, it hurts. You try to change the situation. Then, you accept it. And eventually, you even find an advantage in it.
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That day, I sat at my desk, watching as my male colleagues swarmed around our new coworker, Claire.
She was obviously attractive, so their reaction wasn’t surprising. But when Mark approached her, the others quickly backed off.
I let out a quiet chuckle as I watched. Mark was the most handsome and charismatic man in the office—I was convinced even other men wouldn’t mind if he took them to bed.
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He flirted with Claire, and she giggled at his jokes, twirling a strand of her blonde hair around her finger.
At that moment, Anthony, my boss, approached me. “Sara, do you remember our new project?” he asked, glancing at the laptop screen in front of me.
“Yes, of course. I’m leading it,” I replied, adjusting my glasses.
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“I’m counting on you,” Anthony said with a nod, his tone full of expectation.
I worked at an IT company, and we were launching a new dating app. Anthony had chosen me to lead the project because, no matter how unnoticeable I was, my work results were the best.
He had also offered me an opportunity to work abroad at one of our other branches, but I declined, even though the salary would have been much higher.
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During lunch, I noticed an irritated Mark walking up to Anthony. Curious about what had upset our golden boy this time, I decided to eavesdrop.
“Who did you assign the dating app to?” Mark asked, his voice laced with disbelief.
“Sara. Is there a problem?” Anthony replied, sounding amused.
“Sara? We don’t have anyone by that name,” Mark scoffed, and I felt my jaw tighten.
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“She’s sitting right over there,” Anthony said, pointing at me. I continued pretending not to hear them, keeping my eyes fixed on my screen.
“I thought I’d be handling the dating app. This isn’t fair,” Mark protested, folding his arms across his chest.
“To my office. Now,” Anthony ordered.
I finished my lunch just in time to see Mark walking out of Anthony’s office, looking pleased with himself.
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I had no idea what they had discussed, but no one had told me I was off the project, so I remained calm, though a tiny seed of doubt had been planted in my mind.
The next day, Mark approached me with his signature smile, hovering over my desk like a shadow. I gave him a questioning look.
“Sonia…” he began, leaning in slightly.
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“Sara,” I corrected him, not bothering to hide my irritation.
“Right. Sara.” He chuckled, as if amused by his own mistake. “Want to grab lunch together?” he asked, his voice dripping with casual charm.
“I already ate,” I replied flatly, typing away at my keyboard.
“Then how about a drink after work?” he suggested, tilting his head.
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I turned to face him. “You didn’t even know my name a minute ago. I bet you didn’t even know I worked here,” I said, recalling his conversation with Anthony. “What’s this really about?”
“I just thought it’d be nice to hang out with a lovely colleague,” Mark said smoothly, flashing that infamous smirk that made other women melt.
I scoffed.
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“Oh, come on. It’ll be fun,” he insisted, his persistence almost amusing.
“I have a lot of work,” I said, turning back to my computer.
Mark lingered for a moment before sighing and walking away, but I could feel his eyes on me for a few seconds longer than necessary.
As usual, I stayed late at the office. But when I finally looked up from my screen, I was surprised to see Mark still there. Normally, by the time I finished, the office was empty.
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I stood up, gathered my things, and headed to the elevator. Mark did the same. He followed me, and the whole thing felt strange.
We stepped into the elevator, and it started moving. Then, suddenly, it stopped.
“What’s going on? Are we stuck?” I asked, pressing a few buttons.
“Looks like it,” Mark replied, stuffing his hands into his pockets.
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I pressed the emergency button and explained the situation. The response came: we’d have to wait about two hours.
Mark sighed and sat on the floor, stretching his legs out in front of him. After a moment, I did the same.
“So, tell me about yourself,” he said, tilting his head toward me.
“What?” I chuckled, raising an eyebrow.
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“What’s funny?” he asked, looking genuinely confused.
“Come on, I’ve worked here for years, and most people don’t even know I exist. Why the sudden interest?” I asked, crossing my arms.
“I’m just curious,” he said, shrugging.
“Then why don’t you tell me about yourself?” I countered, narrowing my eyes.
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“Oh, please. You probably know everything about me already,” Mark smirked. “Everyone does.”
That made me laugh again. “That confidence.”
“What? Is that a bad thing?” he asked, grinning.
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“No, not if it’s real. But being invisible has given me an advantage—I notice things. And you, Mark, are nothing but an act. A performer trying to mask his insecurities with fake confidence. So what’s behind all of it? Daddy issues? Mommy didn’t pay attention to you?” I asked, leaning back against the wall.
“Oh, screw you,” he muttered, rolling his eyes.
We sat in silence for a while until Mark finally spoke again.
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“My dad left us when I was three. My mom raised me alone. Then, when I was a teenager, he suddenly came back and tried to mold me into his perfect son. I guess I’m still trying to prove something to him,” he admitted, his voice quieter than usual.
“I get it,” I said, my voice softer now.
Mark looked at me curiously.
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“My mom left us. My dad raised me alone. But she never came back. The last time I saw her, I was thirteen. She told me she was ashamed I was her daughter because, at my age, she had been way more popular,” I said, my throat tightening slightly at the memory.
“She’s an idiot,” Mark said, shaking his head. “I asked Anthony about you. You have the best results in the company. I thought I did. And you’re beautiful, even if your lack of confidence hides it.”
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“Guess everyone copes with trauma differently,” I said, managing a small smile.
“Guess so,” Mark replied.
Just then, the elevator started moving again. When we stepped out, Mark grabbed my wrist.
“How about that drink now?” he asked, his voice gentler than before.
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“If you’re going to be the guy from the elevator, then fine. But if you’re putting the mask back on, I’ll pass,” I said, tilting my head slightly.
“I’ll try to be myself,” Mark promised.
And so, we went to a bar. Then the next day. And the next. Before I knew it, we were spending time together every day—even on weekends.
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I saw a different side of Mark. The real him. The one who was afraid of spiders and teared up when a dog died in a movie.
One evening, I couldn’t resist anymore—I kissed him. And the moment I did, I knew it was right. With him, I felt like myself.
One day at the office, I stood outside Anthony’s office and heard voices inside. I hadn’t planned to listen, but I couldn’t help it.
For illustration purposes only. | Source: Midjourney
“I told you—I know how to win someone over,” Mark said.
“I didn’t think Sara would fall for it. But you win—the dating app project is yours,” Anthony replied.
“Thanks, but—” Mark started, but I wasn’t listening anymore.
I turned and rushed to the bathroom, locked the door, and leaned against it. My breath came in quick, uneven bursts. My hands shook. Tears slid down my face before I could stop them.
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He had lied. He had tricked me to take my job. Every moment we had spent together had been a performance. And I was the fool who believed it. Worse—I had started falling for him.
I forced myself to breathe. I couldn’t fall apart now. Not over him.
I wiped my face, fixed my makeup, and straightened my blazer. Then, I walked straight to Anthony’s office.
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“Oh, Sara, I was just about to talk to you,” he said, looking up from his desk.
“I’d like to accept your offer to work abroad. If it’s still available,” I said, keeping my voice steady.
“It is. What changed your mind?” Anthony asked, raising an eyebrow.
“You were right—there are more opportunities for me there,” I said.
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He studied me for a moment. “When can you leave?”
“Tomorrow,” I replied.
“Tomorrow? Are you sure?”
I nodded. “Yes.”
“Alright, I’ll make the arrangements. You can take the rest of the day off to pack.”
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I thanked him and walked out. My hands clenched around my bag. I saw Mark heading toward me.
I didn’t slow down. I grabbed my things and stepped into the elevator before he could reach me.
By morning, I was in a taxi headed to the airport. Music played in my headphones, drowning everything else out.
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I watched the city blur past. Then, in my window, I saw Mark’s car pull up alongside mine.
He motioned for me to roll down the window. I ignored him. He honked. Annoyed, I lowered it.
“What? Are you here to tell me more lies?” I shouted.
“What are you talking about?” he asked.
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“I know about your deal with Anthony. If I fell for you, you’d get the dating app project,” I said.
“No—I mean, yes, that was the deal. But not anymore. Everything changed when I started spending time with you,” Mark said.
“More lies! I can’t believe I fell for you, that I even started to have feelings for you!” I yelled.
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“Really?” Mark asked.
I just rolled up the window and turned away.
A second later, he swerved his car in front of mine, blocking the road. My taxi and other cars behind us came to a halt, their horns blaring in frustration.
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It was chaos. Mark hurried over, pulled open my door, and looked at me desperately.
“Listen to me,” he said. “I turned down the dating app project.”
“Don’t lie,” I said, stepping out of the taxi.
“I’m not lying. It’s the truth,” he insisted. “Please, don’t go.”
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“And why is that?” I asked.
“Because you’re the only person I can be real with. The only one I don’t have to pretend around,” Mark said. “That’s why I won’t let you get on that damn plane.”
“No one asked for your opinion,” I said.
“I’m falling for you too, Sara. Please,” he begged.
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My mind screamed at me to get back in the taxi, go to the airport, and forget Mark.
But my heart had already decided. My feet moved before I could stop them, bringing me closer to him. He pulled me into his arms and kissed me.
“I see you, Sara. And I will never let you feel invisible again,” Mark whispered before kissing me again.
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We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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